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what is human chorionic gonadotropin?
2015-11-23 17:53:00
Human chorionic gonadotropin editing
Human chorionic gonadotropin (hCG) is a glycoprotein secreted by the trophoblast cells of placenta, it is consists of alpha and beta dimeric glycoprotein. Human chorionic gonadotropin (HCG) - alpha beta, synthesized by the combination of the human chorionic gonadotropin (). The molecular weight is 36700. The glycoprotein hormone, FSH (follicle stimulating hormone), LH (Huang Ti hormone) and TSH (thyroid stimulating hormone) and so on. Beta -HCG is similar to -LH, but the last 24 amino acids are not present in -LH.
Function
Human chorionic gonadotropin prescription
Human chorionic gonadotropin prescription
(1) with the function of LH and FSH, to maintain the life of the menstrual corpus, so as to increase the corpus of the corpus;
(2) promoting the conversion of androgen to estrogen, and stimulating the formation of progesterone;
(3) to inhibit the stimulation of lymphocyte phytohemagglutinin (PHA) and human chorionic promote gonadal hormones can be adsorbed on trophoblast cell surface, in order to avoid trophoblast cells is maternal lymphocytes attack;
(4) LH function, in the fetal pituitary secretion of LH, to stimulate the secretion of testosterone in the fetal testis to promote male sex differentiation; also can promote the development of the gonad, the male can stimulate the vitality of the middle cell of the testis, increase the secretion of male hormone (testosterone). In male patients with combined pituitary defects is very important in the treatment, not only can promote gonadal development and male hormone secretion, but also promote the development of secondary sexual characteristics.
(5) TSH receptor binding to the maternal thyroid cells to stimulate thyroid activity.
Change
Human chorionic gonadotropin drugs
Human chorionic gonadotropin drugs
Human chorionic gonadotropin after fertilization and the rapid proliferation of the maternal blood into the eighth week of pregnancy, and then slowly lower concentrations until eighteenth to 20 weeks, and then remain stable. In general, the level of the human chorionic gonadotropin was elevated to the level of 2.5MoM, which was related to Down syndrome. And the average level of DS in patients with DS was only 1.3MoM, which can not be clearly identified. The human chorionic gonadotropin related molecules for DS examination were free of b-hCG and high glucose hCG (H-hCG).
Human chorionic gonadotropin related molecular level is also related to fetal sex, and the level of gonadotropin was significantly increased than that of the male.
Human chorionic gonadotropin is complete all produced by the placenta chorion syncytiotrophoblast. Human chorionic gonadotropin is produced by trophoblast transitional cell and cell body. Human chorionic gonadotropin secretion in the pregnancy after 10-14 days beginning.
Progesterone and normal value
Human chorionic gonadotropin map
Human chorionic gonadotropin map
Below is a list of the normal values of progesterone and HCG during pregnancy. In particular, the mIU is the same as mU, (I is the 'International') in the middle of the MIU. 1u/ml=1000mu/ml=1000mIU/ml
Progesterone (P)
New and old and new old coefficient of normal value of coefficient of determination of normal value of the legal unit of time were a unit
Follicular phase blood 3.18 ~ 0.6ng/ml 0.6 ~ 1.9nmol/L 0.3145
Blood 3.18 ~ 32.2ng/ml 20.7 ~ 102.4nmol/L 0.3145
At 7 weeks, 24.5 weeks,, 3.12, 0.32, 23.7nmol/L 76.4
At 8 weeks, 28.6 weeks,, 3.12, 0.32, 23.7nmol/L 76.4
Follicular phase blood 24.5 + 7.6ng/ml 89.2 3.12 + 24.6nmol/L 0.32
9 to 12 weeks of pregnancy 38 + 13.0ng/ml 118.6 + 3.12 + 40.6nmol/L 0.32
13 to 16 weeks of pregnancy 45.5 + 14.0ng/ml 142 + 3.12 + 43.7nmol/L 0.32
17 to 20 weeks of pregnancy 63.3 + 14.0ng/ml 197.5 + 3.12 + 43.7nmol/L 0.32
21 to 24 weeks of pregnancy 110.9 + 35.7ng/ml 346 + 3.12 + 111.4nmol/L 0.32
25 to 34 weeks of pregnancy 165.3 + 35.7ng/ml 514.8 + 3.12 + 111.4nmol/L 0.32
At 35 weeks, 202 weeks,, 3.12, 0.32, 146.6nmol/L 630.2
<1.0ng/ml 3.18 <3.2nmol/L 0.3145
13 to 36 weeks of gestation 55ng/ml 3.12 171.6nmol/L 0.32
Term pregnancy amniotic fluid 26ng/ml 3.12 81.1nmol/L 0.32
Related information
Mature women because of the fertilized egg moves into the uterus cavity implantation, embryo formation, in the growth and development of fetal, placental syncytiotrophoblast cells produced a large number of human chorionic gonadotropin (human chorionic gonadotropin, hCG), through the maternal blood circulation and excretion in the urine. HCG levels in serum and urine increased rapidly during 1 to 2.5 weeks, and reached a peak at eighth weeks, and reached to the middle level at fourth months.
Change editor
Human chorionic gonadotropin drugs
Human chorionic gonadotropin drugs
Human chorionic gonadotropin after fertilization and the rapid proliferation of the maternal blood into the eighth week of pregnancy, and then slowly lower concentrations until eighteenth to 20 weeks, and then remain stable. In general, the level of the human chorionic gonadotropin was elevated to the level of 2.5MoM, which was related to Down syndrome. And the average level of DS in patients with DS was only 1.3MoM, which can not be clearly identified. The human chorionic gonadotropin related molecules for DS examination were free of b-hCG and high glucose hCG (H-hCG).
Human chorionic gonadotropin related molecular level is also related to fetal sex, and the level of gonadotropin was significantly increased than that of the male.
Human chorionic gonadotropin is complete all produced by the placenta chorion syncytiotrophoblast. Human chorionic gonadotropin is produced by trophoblast transitional cell and cell body. Human chorionic gonadotropin secretion in the pregnancy after 10-14 days beginning.