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How is urea reabsorbed?
2014-12-04 16:05:04

 

Urea (NH2)2CO is a chemical that comes from the breakdown of proteins. It is the main source of Nitrogen in urine and is excreted by the body as a waste product from your kidneys. Urea is a readily available source of Nitrogen so is used as a fertilizer and sometimes as a supplement to feed for stock. 
 
40-50 % of filtered urea is reabsorbed through passive diffusion in the Proximal Convoluted Tubules. Loop of Henle, Distal Convoluted Tubules and Cortical Collecting Ducts are impermeable to urea. But secretion of urea happens in descending Loop of Henle (This helps to maintain the osmotic gradient in the medulla of the Kidney). There is also re-absorption of urea in the medullary collecting ducts.
 
Urea is a waste product. It is synthesized from waste ammonia by the liver as a way to remove nitrogen from the body without changing the pH of body fluids. It travels to the kidneys, where it assists with osmotic action, and is eventually expelled in urine.